Mastocytosis: typical symptoms
Mastocytosis is a disease with a thousand faces - in some patients the symptoms are very low, whereas other patients suffering from serious ailments. To which Symptoms it in detail comes, depends on
the mast cells are each increased.
The Symptoms of mastocytosis may range from simple fatigue and mild skin irritation and abdominal pain and vomiting. Mostly, however, the symptoms point to the skin surface.
In extreme cases, but sufferers can have a circulatory collapse and (anaphylactic shock) - for example, if they are stung by a wasp.
The brown-red spots on the skin are among the most noticeable symptoms of mastocytosis. The diameter of these spots range from three millimeters (mostly adults) to several centimeters (in children). If you rub on the spots, usually arises an itch on the affected part of the body. In the further course of mastocytosis a reddish rash develops in the form of wheals.
These lesions occur not only in pure Hautmastozytose on, but are also common in the systemic mastocytosis to find. at more than 90 percent of people with systemic mastocytosis also small brown to red-brown stains form on the skin.
In severe Hautmastozytose and indolent systemic mastocytosis may occur general malaise when many mast cells simultaneously distribute their ingredients. These include symptoms
The severity of symptoms can vary greatly. Some sufferers may develop no symptoms for many years - only in special situations, such as severe stress or after enjoying sumptuous meals or alcohol, and after taking some medication, the symptoms show.
At about 10 to 30 percent of patients with systemic mastocytosis in the further course of the disease, bone mass gradually decreases (so-called. Osteopenia) or osteoporosis developed.
The rare aggressive forms of systemic mastocytosis can use serious symptoms accompanied, mostly related to the internal organs and not the skin. This is the case when the mast cells displace the healthy cells of the affected organs (especially the liver, spleen and lymph nodes) and disrupt their function. As a result, the organs enlarge or they fail completely.