liver function tests
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the designation "liver function tests" stands for the concentration of certain enzymes in the blood. Even if it comes spontaneously one or the other in the head: to connect the liver necessarily associated with liver damage due to excessive alcohol consumption, is not correct. Although alcohol abuse is a potential cause of increased liver enzymes. but the liver values rise as well in a variety of other diseases not related to excessive alcohol consumption.
Liver function tests are among the often obtained laboratory values. the doctor will determine the liver function tests, it is all about four enzymes:
What many do not know: GOT, gamma-GT and AP occur in almost all organs - they are by no means typical of the liver. The GPT is found, however, especially in the liver. In many cases, causes a disease of the liver that the values climb.
The doctor determines the liver function tests, in order to better classify which organ is affected, or what health condition could exist. The expression "liver function tests" stresses that the concentration of these enzymes indicative of liver disease.
To determine the liver function tests, the doctor takes blood from a vein (usually in the armpit). Whether elevated liver function tests need to be further clarified, also depends on the lab results: Are the liver just a little too high and result no other evidence of disease, it may be that the doctor wants to control the values only at certain intervals.
If the liver function tests far too high or there are other reasonable suspicion of a disease should further investigations made in order to clarify the cause. a detailed talk is an important part of the investigation:
These and other questions allow doctors and patients to uncover causes or risk factors for liver disease. Also important is a physical Examination, wherein the doctor samples the belly and thus determines the shape, size and condition of the liver. He also checks to see if there are signs of liver disease on the skin, the so-called Liver skin sign. These include, for example, certain vascular networks: the vascular spiders (punctate, red vascular nodules on outbound fine veins, also called spider angiomas). Also blushed palms (palmar erythema) or smooth, shiny-red lips and tongue (paint lips, tongue coating) are among the Liver skin sign.
Furthermore, there may be a yellowing of the skin come (jaundice) in liver damage. Scratch marks may indicate an associated itching. In men, found in liver damage also often a so-called belly baldness where the hair goes down on his stomach, and a growth of mammary glands (gynecomastia).
An ultrasound examination of the liver and other abdominal organs provides further information about the possible reason for increased liver function tests. Ultimately brings a sample of tissue (liver biopsy) certainty what is behind the increase. Whichever approach the doctor and patient decide depends on the individual case.
The Abbreviations the enzymes are available for the following names:
The normal values for the four liver values are for adults at about (measured in blood serum):
* Values for the laboratory measurement with the addition of pyridoxal phosphate
Besides GOT, GPT, GGT and alkaline phosphates also include other proteins, which produces the liver, the liver values. For example:
In hepatic impairment, the concentration of these proteins in the blood decreases and can cause discomfort. Lacks clotting factors, for example, is an increased risk of bleeding.
Another liver value of the bile pigment bilirubin. Bilirubin is produced in the breakdown of red blood pigment hemoglobin. In various diseases of the liver, biliary tract and blood increases bilirubin in the blood. Above a certain concentration, bilirubin is deposited in the tissue. The possible result is jaundice (jaundice), in which the skin and mucous membranes color yellow.