Crohn’s disease: Inflammatory Bowel & shy; disease
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to have Crohn's disease is often lifelong ailments like diarrhea and crampy abdominal pain, which typically occur in batches. With proper treatment, most sufferers are indeed free of symptoms. Complete recovery is so far not possible.
Crohn's disease is a chronic inflammation of the digestive tract, the most spasmodically runs and non-infectious is. Doctors believe the disease with other recurring and partly persistent intestinal inflammation under the term inflammatory bowel disease (IBD) together.
Overall, about 70 percent of people with Crohn's disease have liquid or watery stools over again. The abdominal pain occurs concomitantly to the diarrhea - usually is cramping pain in the right lower abdomen.
Typical of Crohn's disease gastrointestinal symptoms can strengthen, if at the same time there is an allergy or a non-allergic intolerance (intolerance) to specific foodstuffs. Both occurs more often in people with inflammatory bowel disease (IBD).
Rarely the chair blood or mucus is added. However, the diarrhea worry Crohn's disease for other symptoms: By the diarrhea, the body loses a lot of protein and the associated energy loss and weight. Sufferers feel tired, cut off and have no appetite. They often feel a general malaise.
Besides occur in Crohn's disease often the following symptoms on:
Other sections are more rarely affected (less than 5 percent). Crohn's disease can simultaneously several intestinal segments infested separated by healthy portions. Doctors refer in such a pattern of involvement by a segmental, discontinuous infestation.
What Crohn's disease has its causes, is still unknown. The same applies to the chronic intestinal inflammation called ulcerative colitis. In both cases likely to act several factors simultaneously as a trigger for the inflammatory bowel disease.
One factor that plays an important role in the development of Crohn's disease, hereditary predisposition. On the one hand the intestinal inflammation occurs in some families more frequently. Secondly, has about half of people with Crohn's disease specific changes at the genetic trait (known. Mutations in the gene called NOD2 / CARD15, which is located on chromosome 16 of the human genome) on.
In addition, other genes are known which are associated with an increased risk for Crohn's disease. All these risk genes influence the interaction between intestinal flora and gut. It is true to the intestinal flora as an important trigger of chronic intestinal inflammation.
is doing a responsible impaired barrier function of the intestinal mucosa. Normally, the intestinal barrier prevents bacteria penetrate from the intestine into the intestinal wall. Can the intestinal bacteria overcome this barrier, they trigger a strong immune response in the intestinal wall. Because the body absorbs the invading bacteria perceive as pathogens, even if they are not sickening. To ward off these, the body activates various inflammatory cells. The result is typical of Crohn's disease intestinal inflammation.
In addition to hereditary factors following influences may possibly cause Crohn's disease (with):
For a long time it was suspected behind Crohn's disease also psychological causes. However, this is according to current knowledge as locked out. Recognized is, however, that psychological factors can influence the chronic bowel disease in its course: How can emotional stress - such as conflict or stress - trigger prematurely new flare-ups or exacerbate an existing boost.
Each year, doctors in Germany at about 6 of 100,000 Population Crohn's disease resistant. In the last 20 years the number of cases has increased overall. Men and women are equally affected.
The inflammatory bowel disease occurs at any age before, even in children: Each year develop in this country up to 1,500 children a Crohn's disease. but on common the disease begins between 15 and 35 years of age.
In Crohn's disease, several studies are necessary for diagnosis. It starts with the so-called Anamnesis. Here, the doctor asked about the previous complaints. This is followed by physical examination: In Crohn's disease the doctor can reveal existing complications here might like:
Imaging and laboratory tests make it possible to diagnose Crohn's disease safely and distinguish it from other inflammatory bowel disease (IBD). For the diagnosis include:
If the doctor finds signs of Crohn's disease in the colonoscopy in the colon, it is advisable to examine the small intestine and the rest of the digestive tract.
In any case, drugs Crohn's disease is an important part of therapy. There are several means available - which are in any form best suited depends to a large extent on,
Primarily to drug therapy of Crohn's disease
Crohn's disease can strain mentally strong. Therefore a psychosomatic care can concomitantly be useful - especially if
Depending on which complaints Crohn's disease causes outside of the intestine, additional measures may be needed if the intestinal inflammation example, leads to iron deficiency and thus to anemia (anemia), this can be treated by iron supplements.
In addition, Crohn's disease makes the passage of time often surgical treatment necessary.
Prepares Crohn's disease, acute intestinal disorders, treatment consists first of the stop diarrhea by medication. Effective anti-diarrheal agents are the so-called antidiarrheals (e.g., loperamide).
Against a acute Crohn's thrust also come anti-inflammatory drugs for use. Various anti-inflammatory drugs are available.
Infliximab and adalimumab can in severe cases help when azathioprine and corticosteroids in Crohn's disease is not sufficiently effective. The two funds are among the so-called biologics. That is, their structure is similar to the body's own antibodies which are anti-inflammatory.
Used regularly infliximab and adalimumab can help to heal the inflammation-induced damage to the intestinal mucosa. Thus, operations and related hospitalizations for Crohn's disease are rarely necessary. In addition, further therapy may come from without corticosteroids.
Even if the acute symptoms subsided have a therapy with anti-inflammatory medication is useful in Crohn's disease: The use of certain anti-inflammatory drugs for a longer period recommended by another to prevent relapses respectively postpone the next thrust. are particularly effective here azathioprine or 6-mercaptopurine. Advisable is a perennial treatment (at least 4 to 5 years).
If other measures in Crohn's disease Not sufficient to therapy, it is advisable to undergo a surgery considered. This is especially true for children and adolescents whose growth or their puberty is delayed as a result of inflammatory bowel disease.
The first operation is mostly in Crohn's disease (80%) ten years after onset of the disease instead. The most common reasons for this are complications. Absolutely necessary, surgery is at:
The operation is limited to the affected part of the intestine usually. Although inflammation in the remaining intestine is, the operator does not move it to, as long as the intestinal inflammation causes no symptoms, because: When Crohn's disease is an operation in the large intestine is removed, as rather unnecessary and detrimental was found.
Because of possible complications it is advisable for Crohn's disease in the following cases to postpone as long as possible surgery:
Crohn's disease also diet plays an important role. One reason is the increased risk of malnutrition: this can worsen the disease process and thus your quality of life right up to life expectancy.
That is why in malnutrition due to Crohn's disease nutritional therapy recommended by a nutrition medically trained doctor or other qualified professional. If you are missing only a few nutrients (for example, certain vitamins) can be eliminated by appropriate supplement the deficiency.
During an acute Crohn's thrust can be a artificial feeding help: either a venous catheter or a stomach, small intestine or duodenum probe. The nutrition through a tube has opposite the venous catheter two advantages: firstly attributable complications such as phlebitis. On the other hand, the risk of thrombosis, which is elevated in chronic intestinal inflammation, lower.
Once the symptoms of Crohn's nudge subside, you can get used to your gastrointestinal tract gradually returning to a normal diet. Here is a slow food intake recommended:
On too fresh fruit and green salads you must not do without because of Crohn's disease: they are well tolerated by most sufferers. The light normal diet provides the body usually sufficient with all essential nutrients. Many people with Crohn's choose this diet form because it relieves the digestive organs and the entire metabolic system.
However it is advisable to remove sugary products in Crohn's disease from the diet as much as possible. Also, white flour products can adversely affect the course of bowel disease. Lots of fiber, however, relieve uncomfortable symptoms in most cases because they have a favorable effect on digestion. But: If you already extensive intestinal strictures (stenosis) have, it is advisable to refrain from high-fiber foods.
Crohn's disease is a chronic Disease, during which the disease activity usually spasmodically increases and decreases again. In almost half of all cases multiple surgical procedures are necessary. Who it, however, manage to cope with stress and possible depressive symptoms, which can positively influence the course of disease.
Since Crohn's disease runs from person to person, a general prognosis is difficult. It is clear that the intestinal inflammation hardly limits the life expectancy. Most of those affected, one in spite of the disease normal life lead and remain operational.
However, in people with Crohn's disease of the total rare small bowel cancer occurs more frequently than in people without the chronic inflammatory bowel disease.
Crohn's disease can occur in the course to various complications. Primarily, they concern the intestine. Examples are:
Crohn's disease can also cause complications outside of the intestine lead - but this happens rarely. To sites outside of the intestine, to which the inflammatory bowel disease can affect include:
Crohn's disease can hardly prevent, as actual causes of bowel disease are not yet clarified.
However translucent breast-feeding to be a possibility to reduce the risk of developing Crohn's disease: People who have had a baby breast milk develop significantly less likely to Crohn's disease than those in which only bottle feeding was used.
Competence Network Bowel Disease
The Competence Network Inflammatory Bowel Disease e.V. is a research organization that offers, among other things, information about Crohn's disease and ulcerative colitis.
The Cröhnchen club
The Cröhnchen Club is a lively support group for all Cedler with MC, CU or other intestinal diseases. The group exchanges views via email, forum and chat.
German Ernährungsberatungs- Information Network (DEBInet)
Other important information and examples of well-tolerated and inappropriate foods for patients with Crohn's disease.
A different forum for patients and their relatives of Crohn's disease, ulcerative colitis, stoma and all related forms of IBD (inflammatory bowel disease).