Testicular Cancer: Causes and risk factors

21 October 2017

The causes of testicular cancer are still not clear. However, since ill especially younger men from Experts believe that the basis is scheduled for a later testicular cancer already during embryonic development in the womb. At this stage in the testis of an unborn boy damaged germ cells can occur, so-called progenitor cells. By the hormone boost in puberty, these are capitalized and develop themselves real cancer cells continue. Not yet known external trigger then worry later that proliferate in cancer cells and a malignant tumor ensteht.

Why develop the germ cells of an unborn child to progenitor cells of testicular cancer is not yet clear. May play hereditary factors or low displacements of the hormone balance the pregnant woman or the unborn child a role: An increased number of female hormones (estrogen) can intervene in the development of the testes and germ cells of the embryo and change it.

The Hormonal balance pregnant women may shift among others

Progenitor cells of testicular cancer develop later in life not necessarily to a malignant tumor. However, there are known some factors that increase the risk for proven.

These risk factors for the onset of testicular cancer are:

The main risk factor for testicular cancer is a Undescended testicles. This is a physical developmental disorder: Normally, the testicles are moving from the second month of the embryo from the abdominal cavity into the scrotum. These testes hike is mostly finished with the first year of life. If the process is disturbed, and there remains a testis in an incorrect position in the abdomen or in the groin area, is called an undescended testis.

Undescended testis should be corrected within the first two years of life by an operation - even to the later procreative not to jeopardize a boy. Such a premature engagement lowers Moreover, the risk of developing later on testicular cancer. However, compared with the general population, it remains elevated.

hereditary factors are also a cause of increased testicular cancer risk. In some families, this disease occurs more frequently: ill man with testicular cancer, so the risk of his brothers, also to develop a malignant testicular tumor, a 12-fold increase; is a father of testicular cancer diagnosed, the risk of testicular cancer increases his sons also.

In addition, men who have already had a malignant tumor in a testicle have a higher risk of developing a tumor in the other testicle. More generally also fair-skinned Europeans are more often affected by testicular cancer than African-born men.


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