Celiac Disease: Overview
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Celiac disease (celiac sprue) is distributed worldwide and can cause unpleasant symptoms such as diarrhea, nausea and a bloated belly. Especially in children, the disturbed intestinal function lead to malnutrition and thus growth and development disorders.
In Europe, an estimated ill 1 of 70 to 200 people celiac disease. Screening studies in Germany have shown that while approximately every 3 to 4 person has specific risk genes for celiac disease, but only less than 5 percent of those affected develop the full picture of the disease. In adulthood, women are affected slightly more often than men.
Because of the genetic component, there is a family history, identical twins diagnosed with a probability of 75 percent together on celiac disease.
You can find more information about celiac disease:
Other symptoms may include:
in the Childhood or in infancy celiac disease can lead to malnutrition. This in turn causes:
The full screen but of celiac disease and related symptoms occur in only about 10 to 20 percent of those affected. 8 to 9 of 10 victims, however, have no or very non-specific symptoms and therefore do not even know that they have celiac disease.
Celiac disease is using the endoscopy a clear diagnosis possible: the small intestine is then examined with an endoscope to changes. In the native sprue specific structures of the small intestine, which serve to better absorption of nutrients are - the so-called villi - greatly reduced or no longer present, so that the absorption of certain nutrients can not be done at all or only to a limited extent. This may be the doctor notice with the endoscope, a tube-shaped instrument with a small camera on the end and tissue samples secure (biopsy).
In addition, a proof of antibodies confirm the diagnosis in the blood. The higher the measured value of specific antibody, the stronger the small intestinal mucosa is damaged. Therefore, the antibody value shows the extent of disease and helps to monitor the development of the indigenous sprue or celiac disease.
On examination of blood parameters show up in celiac disease often certain changes:
These blood values associated with corresponding complaints a Indication of a possible celiac sprue give; only so is not sufficient for a reliable diagnosis, as these changes in the blood count can also occur in other diseases.
For an accurate diagnosis certain function tests necessary, which verify the ability of the small intestine for absorption or utilization of nutrients:
Celiac disease can not be treated with Mediakamenten or cured. Anyone who has celiac disease has to live long gluten-containing foods avoid. This includes Rye, wheat, barley and spelled Products and products thereof, such as bread, cakes, pasta, bread crumbs, cereals, beer and more. Particular caution should be exercised in finished products (sauces, soups, canned food, meat, etc.), often hidden gluten contain.
Even small exceptions to the gluten-free diet quickly solve again symptoms and may increase over time, the incidence of colorectal cancer and other cancers, especially malignant Lypmhknotenvergrößerungen (malignant lymphoma). Celiac disease is Cancer risk but only slightly increased if the gluten-free diet consistently is maintained.
Often it makes sense at the beginning of therapy not only to pay attention to a gluten-free diet, but also milk and milk products to renounce, because the damaged intestinal mucosa can produce in sufficient quantities often the lactose-degrading enzyme lactase not or not. Has a lactose test revealed that the person does not tolerate milk sugar (lactose), he should avoid dairy products until bowel function is restored. Then the intestine often produces enough lactase again. If no lactase deficiency detected, it is not necessary to give up milk.
In celiac come as causes genetic investments questioned, leading to a Autoimmune reaction to lead. Gluten triggers an immune complex of (similar to a allergy). The cells of the small intestine absorb the gluten. There, it activates the immune system, which fights the gluten. The immune response causes Inflammation in the cells of the small intestine forth that causes them to die.
Other possible causes of celiac disease experts discuss enzyme defects in the small intestinal mucosa.
celiac disease runs with consistent gluten-free nutrition Good. Affected children develop physically and mentally completely normal with appropriate therapy.
without treatment leads the celiac childhood in the further course to
Other consequences of the native sprue can be:
In adulthood the likelihood of developing cancer or osteoporosis increases. Recent studies, however, indicate that the risk of cancer to normal when the parties involved are consistently feed gluten free.
Celiac disease can not prevent. Screening tests in newborns are not prescribed. When symptoms occur, a diagnosis should be done, however, at an early stage in order to avoid serious deficiencies.
You can not prevent celiac disease also by fundamentally gluten-free diet. Who does not have celiac sprue, can take gluten-containing foods, without thereby increasing the risk of disease.
The after-effects of the native sprue although you can prevent by themselves from diagnosis consistently gluten free malnourished. In addition, there are a few recommendations, with which one can prevent potentially severe cases of celiac disease already in infants, for example: